SARS coronavirus accessory proteins
Identifieur interne : 000F05 ( Pmc/Checkpoint ); précédent : 000F04; suivant : 000F06SARS coronavirus accessory proteins
Auteurs : Krishna Narayanan ; Cheng Huang ; Shinji MakinoSource :
- Virus Research [ 0168-1702 ] ; 2007.
Abstract
The emergence of the severe acute respiratory syndrome coronavirus (SARS-CoV) has led to a renewed interest in studying the role of accessory proteins in regulating coronavirus infections in the natural host. A significant body of evidence has accumulated in the area of SARS-CoV and host interactions that indicate that the accessory proteins might play an important role in modulating the host response to virus infection and thereby, contribute to pathogenesis. In this review, we have compiled the current knowledge about SARS-CoV accessory proteins, obtained from studies in cell culture systems, reverse genetics and animal models, to shed some light into the possible role of these proteins in the propagation and virulence of SARS-CoV in its natural host. We conclude by providing some questions for future studies that will greatly advance our knowledge about the biological significance and contributions of the accessory proteins in the development of SARS in humans.
Url:
DOI: 10.1016/j.virusres.2007.10.009
PubMed: 18045721
PubMed Central: 2720074
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
PMC:2720074Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">SARS coronavirus accessory proteins</title><author><name sortKey="Narayanan, Krishna" sort="Narayanan, Krishna" uniqKey="Narayanan K" first="Krishna" last="Narayanan">Krishna Narayanan</name></author><author><name sortKey="Huang, Cheng" sort="Huang, Cheng" uniqKey="Huang C" first="Cheng" last="Huang">Cheng Huang</name></author><author><name sortKey="Makino, Shinji" sort="Makino, Shinji" uniqKey="Makino S" first="Shinji" last="Makino">Shinji Makino</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">18045721</idno><idno type="pmc">2720074</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720074</idno><idno type="RBID">PMC:2720074</idno><idno type="doi">10.1016/j.virusres.2007.10.009</idno><date when="2007">2007</date><idno type="wicri:Area/Pmc/Corpus">001915</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001915</idno><idno type="wicri:Area/Pmc/Curation">001915</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001915</idno><idno type="wicri:Area/Pmc/Checkpoint">000F05</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000F05</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">SARS coronavirus accessory proteins</title><author><name sortKey="Narayanan, Krishna" sort="Narayanan, Krishna" uniqKey="Narayanan K" first="Krishna" last="Narayanan">Krishna Narayanan</name></author><author><name sortKey="Huang, Cheng" sort="Huang, Cheng" uniqKey="Huang C" first="Cheng" last="Huang">Cheng Huang</name></author><author><name sortKey="Makino, Shinji" sort="Makino, Shinji" uniqKey="Makino S" first="Shinji" last="Makino">Shinji Makino</name></author></analytic><series><title level="j">Virus Research</title><idno type="ISSN">0168-1702</idno><idno type="eISSN">1872-7492</idno><imprint><date when="2007">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The emergence of the severe acute respiratory syndrome coronavirus (SARS-CoV) has led to a renewed interest in studying the role of accessory proteins in regulating coronavirus infections in the natural host. A significant body of evidence has accumulated in the area of SARS-CoV and host interactions that indicate that the accessory proteins might play an important role in modulating the host response to virus infection and thereby, contribute to pathogenesis. In this review, we have compiled the current knowledge about SARS-CoV accessory proteins, obtained from studies in cell culture systems, reverse genetics and animal models, to shed some light into the possible role of these proteins in the propagation and virulence of SARS-CoV in its natural host. We conclude by providing some questions for future studies that will greatly advance our knowledge about the biological significance and contributions of the accessory proteins in the development of SARS in humans.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Akerstrom, S" uniqKey="Akerstrom S">S. Akerstrom</name></author><author><name sortKey="Tan, Y J" uniqKey="Tan Y">Y.J. Tan</name></author><author><name sortKey="Mirazimi, A" uniqKey="Mirazimi A">A. Mirazimi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Almazan, F" uniqKey="Almazan F">F. Almazan</name></author><author><name sortKey="Dediego, M L" uniqKey="Dediego M">M.L. Dediego</name></author><author><name sortKey="Galan, C" uniqKey="Galan C">C. Galan</name></author><author><name sortKey="Escors, D" uniqKey="Escors D">D. Escors</name></author><author><name sortKey="Alvarez, E" uniqKey="Alvarez E">E. Alvarez</name></author><author><name sortKey="Ortego, J" uniqKey="Ortego J">J. Ortego</name></author><author><name sortKey="Sola, I" uniqKey="Sola I">I. Sola</name></author><author><name sortKey="Zuniga, S" uniqKey="Zuniga S">S. Zuniga</name></author><author><name sortKey="Alonso, S" uniqKey="Alonso S">S. Alonso</name></author><author><name sortKey="Moreno, J L" uniqKey="Moreno J">J.L. Moreno</name></author><author><name sortKey="Nogales, A" uniqKey="Nogales A">A. Nogales</name></author><author><name sortKey="Capiscol, C" uniqKey="Capiscol C">C. Capiscol</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chan, W S" uniqKey="Chan W">W.S. Chan</name></author><author><name sortKey="Wu, C" uniqKey="Wu C">C. Wu</name></author><author><name sortKey="Chow, S C" uniqKey="Chow S">S.C. Chow</name></author><author><name sortKey="Cheung, T" uniqKey="Cheung T">T. Cheung</name></author><author><name sortKey="To, K F" uniqKey="To K">K.F. To</name></author><author><name sortKey="Leung, W K" uniqKey="Leung W">W.K. Leung</name></author><author><name sortKey="Chan, P K" uniqKey="Chan P">P.K. Chan</name></author><author><name sortKey="Lee, K C" uniqKey="Lee K">K.C. Lee</name></author><author><name sortKey="Ng, H K" uniqKey="Ng H">H.K. Ng</name></author><author><name sortKey="Au, D M" uniqKey="Au D">D.M. Au</name></author><author><name sortKey="Lo, A W" uniqKey="Lo A">A.W. Lo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Curtis, K M" uniqKey="Curtis K">K.M. Curtis</name></author><author><name sortKey="Yount, B" uniqKey="Yount B">B. Yount</name></author><author><name sortKey="Baric, R S" uniqKey="Baric R">R.S. Baric</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Haan, C A" uniqKey="De Haan C">C.A. de Haan</name></author><author><name sortKey="Masters, P S" uniqKey="Masters P">P.S. Masters</name></author><author><name sortKey="Shen, X" uniqKey="Shen X">X. Shen</name></author><author><name sortKey="Weiss, S" uniqKey="Weiss S">S. Weiss</name></author><author><name sortKey="Rottier, P J" uniqKey="Rottier P">P.J. Rottier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fielding, B C" uniqKey="Fielding B">B.C. Fielding</name></author><author><name sortKey="Gunalan, V" uniqKey="Gunalan V">V. Gunalan</name></author><author><name sortKey="Tan, T H" uniqKey="Tan T">T.H. Tan</name></author><author><name sortKey="Chou, C F" uniqKey="Chou C">C.F. Chou</name></author><author><name sortKey="Shen, S" uniqKey="Shen S">S. Shen</name></author><author><name sortKey="Khan, S" uniqKey="Khan S">S. Khan</name></author><author><name sortKey="Lim, S G" uniqKey="Lim S">S.G. Lim</name></author><author><name sortKey="Hong, W" uniqKey="Hong W">W. Hong</name></author><author><name sortKey="Tan, Y J" uniqKey="Tan Y">Y.J. Tan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fielding, B C" uniqKey="Fielding B">B.C. Fielding</name></author><author><name sortKey="Tan, Y J" uniqKey="Tan Y">Y.J. Tan</name></author><author><name sortKey="Shuo, S" uniqKey="Shuo S">S. Shuo</name></author><author><name sortKey="Tan, T H" uniqKey="Tan T">T.H. Tan</name></author><author><name sortKey="Ooi, E E" uniqKey="Ooi E">E.E. Ooi</name></author><author><name sortKey="Lim, S G" uniqKey="Lim S">S.G. Lim</name></author><author><name sortKey="Hong, W" uniqKey="Hong W">W. Hong</name></author><author><name sortKey="Goh, P Y" uniqKey="Goh P">P.Y. Goh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frieman, M" uniqKey="Frieman M">M. Frieman</name></author><author><name sortKey="Heise, M" uniqKey="Heise M">M. Heise</name></author><author><name sortKey="Baric, R" uniqKey="Baric R">R. Baric</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frieman, M" uniqKey="Frieman M">M. Frieman</name></author><author><name sortKey="Yount, B" uniqKey="Yount B">B. Yount</name></author><author><name sortKey="Heise, M" uniqKey="Heise M">M. Heise</name></author><author><name sortKey="Kopecky Bromberg, S A" uniqKey="Kopecky Bromberg S">S.A. Kopecky-Bromberg</name></author><author><name sortKey="Palese, P" uniqKey="Palese P">P. Palese</name></author><author><name sortKey="Baric, R S" uniqKey="Baric R">R.S. Baric</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Geng, H" uniqKey="Geng H">H. Geng</name></author><author><name sortKey="Liu, Y M" uniqKey="Liu Y">Y.M. Liu</name></author><author><name sortKey="Chan, W S" uniqKey="Chan W">W.S. Chan</name></author><author><name sortKey="Lo, A W" uniqKey="Lo A">A.W. Lo</name></author><author><name sortKey="Au, D M" uniqKey="Au D">D.M. Au</name></author><author><name sortKey="Waye, M M" uniqKey="Waye M">M.M. Waye</name></author><author><name sortKey="Ho, Y Y" uniqKey="Ho Y">Y.Y. Ho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B.J. Zheng</name></author><author><name sortKey="He, Y Q" uniqKey="He Y">Y.Q. He</name></author><author><name sortKey="Liu, X L" uniqKey="Liu X">X.L. Liu</name></author><author><name sortKey="Zhuang, Z X" uniqKey="Zhuang Z">Z.X. Zhuang</name></author><author><name sortKey="Cheung, C L" uniqKey="Cheung C">C.L. Cheung</name></author><author><name sortKey="Luo, S W" uniqKey="Luo S">S.W. Luo</name></author><author><name sortKey="Li, P H" uniqKey="Li P">P.H. Li</name></author><author><name sortKey="Zhang, L J" uniqKey="Zhang L">L.J. Zhang</name></author><author><name sortKey="Guan, Y J" uniqKey="Guan Y">Y.J. Guan</name></author><author><name sortKey="Butt, K M" uniqKey="Butt K">K.M. Butt</name></author><author><name sortKey="Wong, K L" uniqKey="Wong K">K.L. Wong</name></author><author><name sortKey="Chan, K W" uniqKey="Chan K">K.W. Chan</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W. Lim</name></author><author><name sortKey="Shortridge, K F" uniqKey="Shortridge K">K.F. Shortridge</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guo, J P" uniqKey="Guo J">J.P. Guo</name></author><author><name sortKey="Petric, M" uniqKey="Petric M">M. Petric</name></author><author><name sortKey="Campbell, W" uniqKey="Campbell W">W. Campbell</name></author><author><name sortKey="Mcgeer, P L" uniqKey="Mcgeer P">P.L. McGeer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haijema, B J" uniqKey="Haijema B">B.J. Haijema</name></author><author><name sortKey="Volders, H" uniqKey="Volders H">H. Volders</name></author><author><name sortKey="Rottier, P J" uniqKey="Rottier P">P.J. Rottier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hsieh, P K" uniqKey="Hsieh P">P.K. Hsieh</name></author><author><name sortKey="Chang, S C" uniqKey="Chang S">S.C. Chang</name></author><author><name sortKey="Huang, C C" uniqKey="Huang C">C.C. Huang</name></author><author><name sortKey="Lee, T T" uniqKey="Lee T">T.T. Lee</name></author><author><name sortKey="Hsiao, C W" uniqKey="Hsiao C">C.W. Hsiao</name></author><author><name sortKey="Kou, Y H" uniqKey="Kou Y">Y.H. Kou</name></author><author><name sortKey="Chen, I Y" uniqKey="Chen I">I.Y. Chen</name></author><author><name sortKey="Chang, C K" uniqKey="Chang C">C.K. Chang</name></author><author><name sortKey="Huang, T H" uniqKey="Huang T">T.H. Huang</name></author><author><name sortKey="Chang, M F" uniqKey="Chang M">M.F. Chang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Ito, N" uniqKey="Ito N">N. Ito</name></author><author><name sortKey="Tseng, C T" uniqKey="Tseng C">C.T. Tseng</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Narayanan, K" uniqKey="Narayanan K">K. Narayanan</name></author><author><name sortKey="Ito, N" uniqKey="Ito N">N. Ito</name></author><author><name sortKey="Peters, C J" uniqKey="Peters C">C.J. Peters</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Peters, C J" uniqKey="Peters C">C.J. Peters</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Yang, Z Y" uniqKey="Yang Z">Z.Y. Yang</name></author><author><name sortKey="Kong, W P" uniqKey="Kong W">W.P. Kong</name></author><author><name sortKey="Nabel, G J" uniqKey="Nabel G">G.J. Nabel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Imbert, I" uniqKey="Imbert I">I. Imbert</name></author><author><name sortKey="Guillemot, J C" uniqKey="Guillemot J">J.C. Guillemot</name></author><author><name sortKey="Bourhis, J M" uniqKey="Bourhis J">J.M. Bourhis</name></author><author><name sortKey="Bussetta, C" uniqKey="Bussetta C">C. Bussetta</name></author><author><name sortKey="Coutard, B" uniqKey="Coutard B">B. Coutard</name></author><author><name sortKey="Egloff, M P" uniqKey="Egloff M">M.P. Egloff</name></author><author><name sortKey="Ferron, F" uniqKey="Ferron F">F. Ferron</name></author><author><name sortKey="Gorbalenya, A E" uniqKey="Gorbalenya A">A.E. Gorbalenya</name></author><author><name sortKey="Canard, B" uniqKey="Canard B">B. Canard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ito, N" uniqKey="Ito N">N. Ito</name></author><author><name sortKey="Mossel, E C" uniqKey="Mossel E">E.C. Mossel</name></author><author><name sortKey="Narayanan, K" uniqKey="Narayanan K">K. Narayanan</name></author><author><name sortKey="Popov, V L" uniqKey="Popov V">V.L. Popov</name></author><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Inoue, T" uniqKey="Inoue T">T. Inoue</name></author><author><name sortKey="Peters, C J" uniqKey="Peters C">C.J. Peters</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kanzawa, N" uniqKey="Kanzawa N">N. Kanzawa</name></author><author><name sortKey="Nishigaki, K" uniqKey="Nishigaki K">K. Nishigaki</name></author><author><name sortKey="Hayashi, T" uniqKey="Hayashi T">T. Hayashi</name></author><author><name sortKey="Ishii, Y" uniqKey="Ishii Y">Y. Ishii</name></author><author><name sortKey="Furukawa, S" uniqKey="Furukawa S">S. Furukawa</name></author><author><name sortKey="Niiro, A" uniqKey="Niiro A">A. Niiro</name></author><author><name sortKey="Yasui, F" uniqKey="Yasui F">F. Yasui</name></author><author><name sortKey="Kohara, M" uniqKey="Kohara M">M. Kohara</name></author><author><name sortKey="Morita, K" uniqKey="Morita K">K. Morita</name></author><author><name sortKey="Matsushima, K" uniqKey="Matsushima K">K. Matsushima</name></author><author><name sortKey="Le, M Q" uniqKey="Le M">M.Q. Le</name></author><author><name sortKey="Masuda, T" uniqKey="Masuda T">T. Masuda</name></author><author><name sortKey="Kannagi, M" uniqKey="Kannagi M">M. Kannagi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Keng, C T" uniqKey="Keng C">C.T. Keng</name></author><author><name sortKey="Choi, Y W" uniqKey="Choi Y">Y.W. Choi</name></author><author><name sortKey="Welkers, M R" uniqKey="Welkers M">M.R. Welkers</name></author><author><name sortKey="Chan, D Z" uniqKey="Chan D">D.Z. Chan</name></author><author><name sortKey="Shen, S" uniqKey="Shen S">S. Shen</name></author><author><name sortKey="Gee Lim, S" uniqKey="Gee Lim S">S. Gee Lim</name></author><author><name sortKey="Hong, W" uniqKey="Hong W">W. Hong</name></author><author><name sortKey="Tan, Y J" uniqKey="Tan Y">Y.J. Tan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khan, S" uniqKey="Khan S">S. Khan</name></author><author><name sortKey="Fielding, B C" uniqKey="Fielding B">B.C. Fielding</name></author><author><name sortKey="Tan, T H" uniqKey="Tan T">T.H. Tan</name></author><author><name sortKey="Chou, C F" uniqKey="Chou C">C.F. Chou</name></author><author><name sortKey="Shen, S" uniqKey="Shen S">S. Shen</name></author><author><name sortKey="Lim, S G" uniqKey="Lim S">S.G. Lim</name></author><author><name sortKey="Hong, W" uniqKey="Hong W">W. Hong</name></author><author><name sortKey="Tan, Y J" uniqKey="Tan Y">Y.J. Tan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kopecky Bromberg, S A" uniqKey="Kopecky Bromberg S">S.A. Kopecky-Bromberg</name></author><author><name sortKey="Martinez Sobrido, L" uniqKey="Martinez Sobrido L">L. Martinez-Sobrido</name></author><author><name sortKey="Frieman, M" uniqKey="Frieman M">M. Frieman</name></author><author><name sortKey="Baric, R A" uniqKey="Baric R">R.A. Baric</name></author><author><name sortKey="Palese, P" uniqKey="Palese P">P. Palese</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kopecky Bromberg, S A" uniqKey="Kopecky Bromberg S">S.A. Kopecky-Bromberg</name></author><author><name sortKey="Martinez Sobrido, L" uniqKey="Martinez Sobrido L">L. Martinez-Sobrido</name></author><author><name sortKey="Palese, P" uniqKey="Palese P">P. Palese</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kumar, P" uniqKey="Kumar P">P. Kumar</name></author><author><name sortKey="Gunalan, V" uniqKey="Gunalan V">V. Gunalan</name></author><author><name sortKey="Liu, B" uniqKey="Liu B">B. Liu</name></author><author><name sortKey="Chow, V T" uniqKey="Chow V">V.T. Chow</name></author><author><name sortKey="Druce, J" uniqKey="Druce J">J. Druce</name></author><author><name sortKey="Birch, C" uniqKey="Birch C">C. Birch</name></author><author><name sortKey="Catton, M" uniqKey="Catton M">M. Catton</name></author><author><name sortKey="Fielding, B C" uniqKey="Fielding B">B.C. Fielding</name></author><author><name sortKey="Tan, Y J" uniqKey="Tan Y">Y.J. Tan</name></author><author><name sortKey="Lal, S K" uniqKey="Lal S">S.K. Lal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lai, M M" uniqKey="Lai M">M.M. Lai</name></author><author><name sortKey="Cavanagh, D" uniqKey="Cavanagh D">D. Cavanagh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Law, H K" uniqKey="Law H">H.K. Law</name></author><author><name sortKey="Cheung, C Y" uniqKey="Cheung C">C.Y. Cheung</name></author><author><name sortKey="Ng, H Y" uniqKey="Ng H">H.Y. Ng</name></author><author><name sortKey="Sia, S F" uniqKey="Sia S">S.F. Sia</name></author><author><name sortKey="Chan, Y O" uniqKey="Chan Y">Y.O. Chan</name></author><author><name sortKey="Luk, W" uniqKey="Luk W">W. Luk</name></author><author><name sortKey="Nicholls, J M" uniqKey="Nicholls J">J.M. Nicholls</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Lau, Y L" uniqKey="Lau Y">Y.L. Lau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Law, P T" uniqKey="Law P">P.T. Law</name></author><author><name sortKey="Wong, C H" uniqKey="Wong C">C.H. Wong</name></author><author><name sortKey="Au, T C" uniqKey="Au T">T.C. Au</name></author><author><name sortKey="Chuck, C P" uniqKey="Chuck C">C.P. Chuck</name></author><author><name sortKey="Kong, S K" uniqKey="Kong S">S.K. Kong</name></author><author><name sortKey="Chan, P K" uniqKey="Chan P">P.K. Chan</name></author><author><name sortKey="To, K F" uniqKey="To K">K.F. To</name></author><author><name sortKey="Lo, A W" uniqKey="Lo A">A.W. Lo</name></author><author><name sortKey="Chan, J Y" uniqKey="Chan J">J.Y. Chan</name></author><author><name sortKey="Suen, Y K" uniqKey="Suen Y">Y.K. Suen</name></author><author><name sortKey="Chan, H Y" uniqKey="Chan H">H.Y. Chan</name></author><author><name sortKey="Fung, K P" uniqKey="Fung K">K.P. Fung</name></author><author><name sortKey="Waye, M M" uniqKey="Waye M">M.M. Waye</name></author><author><name sortKey="Sung, J J" uniqKey="Sung J">J.J. Sung</name></author><author><name sortKey="Lo, Y M" uniqKey="Lo Y">Y.M. Lo</name></author><author><name sortKey="Tsui, S K" uniqKey="Tsui S">S.K. Tsui</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leong, W F" uniqKey="Leong W">W.F. Leong</name></author><author><name sortKey="Tan, H C" uniqKey="Tan H">H.C. Tan</name></author><author><name sortKey="Ooi, E E" uniqKey="Ooi E">E.E. Ooi</name></author><author><name sortKey="Koh, D R" uniqKey="Koh D">D.R. Koh</name></author><author><name sortKey="Chow, V T" uniqKey="Chow V">V.T. Chow</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, W" uniqKey="Lu W">W. Lu</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B.J. Zheng</name></author><author><name sortKey="Xu, K" uniqKey="Xu K">K. Xu</name></author><author><name sortKey="Schwarz, W" uniqKey="Schwarz W">W. Schwarz</name></author><author><name sortKey="Du, L" uniqKey="Du L">L. Du</name></author><author><name sortKey="Wong, C K" uniqKey="Wong C">C.K. Wong</name></author><author><name sortKey="Chen, J" uniqKey="Chen J">J. Chen</name></author><author><name sortKey="Duan, S" uniqKey="Duan S">S. Duan</name></author><author><name sortKey="Deubel, V" uniqKey="Deubel V">V. Deubel</name></author><author><name sortKey="Sun, B" uniqKey="Sun B">B. Sun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marra, M A" uniqKey="Marra M">M.A. Marra</name></author><author><name sortKey="Jones, S J" uniqKey="Jones S">S.J. Jones</name></author><author><name sortKey="Astell, C R" uniqKey="Astell C">C.R. Astell</name></author><author><name sortKey="Holt, R A" uniqKey="Holt R">R.A. Holt</name></author><author><name sortKey="Brooks Wilson, A" uniqKey="Brooks Wilson A">A. Brooks-Wilson</name></author><author><name sortKey="Butterfield, Y S" uniqKey="Butterfield Y">Y.S. Butterfield</name></author><author><name sortKey="Khattra, J" uniqKey="Khattra J">J. Khattra</name></author><author><name sortKey="Asano, J K" uniqKey="Asano J">J.K. Asano</name></author><author><name sortKey="Barber, S A" uniqKey="Barber S">S.A. Barber</name></author><author><name sortKey="Chan, S Y" uniqKey="Chan S">S.Y. Chan</name></author><author><name sortKey="Cloutier, A" uniqKey="Cloutier A">A. Cloutier</name></author><author><name sortKey="Coughlin, S M" uniqKey="Coughlin S">S.M. Coughlin</name></author><author><name sortKey="Freeman, D" uniqKey="Freeman D">D. Freeman</name></author><author><name sortKey="Girn, N" uniqKey="Girn N">N. Girn</name></author><author><name sortKey="Griffith, O L" uniqKey="Griffith O">O.L. Griffith</name></author><author><name sortKey="Leach, S R" uniqKey="Leach S">S.R. Leach</name></author><author><name sortKey="Mayo, M" uniqKey="Mayo M">M. Mayo</name></author><author><name sortKey="Mcdonald, H" uniqKey="Mcdonald H">H. McDonald</name></author><author><name sortKey="Montgomery, S B" uniqKey="Montgomery S">S.B. Montgomery</name></author><author><name sortKey="Pandoh, P K" uniqKey="Pandoh P">P.K. Pandoh</name></author><author><name sortKey="Petrescu, A S" uniqKey="Petrescu A">A.S. Petrescu</name></author><author><name sortKey="Robertson, A G" uniqKey="Robertson A">A.G. Robertson</name></author><author><name sortKey="Schein, J E" uniqKey="Schein J">J.E. Schein</name></author><author><name sortKey="Siddiqui, A" uniqKey="Siddiqui A">A. Siddiqui</name></author><author><name sortKey="Smailus, D E" uniqKey="Smailus D">D.E. Smailus</name></author><author><name sortKey="Stott, J M" uniqKey="Stott J">J.M. Stott</name></author><author><name sortKey="Yang, G S" uniqKey="Yang G">G.S. Yang</name></author><author><name sortKey="Plummer, F" uniqKey="Plummer F">F. Plummer</name></author><author><name sortKey="Andonov, A" uniqKey="Andonov A">A. Andonov</name></author><author><name sortKey="Artsob, H" uniqKey="Artsob H">H. Artsob</name></author><author><name sortKey="Bastien, N" uniqKey="Bastien N">N. Bastien</name></author><author><name sortKey="Bernard, K" uniqKey="Bernard K">K. Bernard</name></author><author><name sortKey="Booth, T F" uniqKey="Booth T">T.F. Booth</name></author><author><name sortKey="Bowness, D" uniqKey="Bowness D">D. Bowness</name></author><author><name sortKey="Czub, M" uniqKey="Czub M">M. Czub</name></author><author><name sortKey="Drebot, M" uniqKey="Drebot M">M. Drebot</name></author><author><name sortKey="Fernando, L" uniqKey="Fernando L">L. Fernando</name></author><author><name sortKey="Flick, R" uniqKey="Flick R">R. Flick</name></author><author><name sortKey="Garbutt, M" uniqKey="Garbutt M">M. Garbutt</name></author><author><name sortKey="Gray, M" uniqKey="Gray M">M. Gray</name></author><author><name sortKey="Grolla, A" uniqKey="Grolla A">A. Grolla</name></author><author><name sortKey="Jones, S" uniqKey="Jones S">S. Jones</name></author><author><name sortKey="Feldmann, H" uniqKey="Feldmann H">H. Feldmann</name></author><author><name sortKey="Meyers, A" uniqKey="Meyers A">A. Meyers</name></author><author><name sortKey="Kabani, A" uniqKey="Kabani A">A. Kabani</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Normand, S" uniqKey="Normand S">S. Normand</name></author><author><name sortKey="Stroher, U" uniqKey="Stroher U">U. Stroher</name></author><author><name sortKey="Tipples, G A" uniqKey="Tipples G">G.A. Tipples</name></author><author><name sortKey="Tyler, S" uniqKey="Tyler S">S. Tyler</name></author><author><name sortKey="Vogrig, R" uniqKey="Vogrig R">R. Vogrig</name></author><author><name sortKey="Ward, D" uniqKey="Ward D">D. Ward</name></author><author><name sortKey="Watson, B" uniqKey="Watson B">B. Watson</name></author><author><name sortKey="Brunham, R C" uniqKey="Brunham R">R.C. Brunham</name></author><author><name sortKey="Krajden, M" uniqKey="Krajden M">M. Krajden</name></author><author><name sortKey="Petric, M" uniqKey="Petric M">M. Petric</name></author><author><name sortKey="Skowronski, D M" uniqKey="Skowronski D">D.M. Skowronski</name></author><author><name sortKey="Upton, C" uniqKey="Upton C">C. Upton</name></author><author><name sortKey="Roper, R L" uniqKey="Roper R">R.L. Roper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mccray, P B" uniqKey="Mccray P">P.B. McCray</name></author><author><name sortKey="Pewe, L" uniqKey="Pewe L">L. Pewe</name></author><author><name sortKey="Wohlford Lenane, C" uniqKey="Wohlford Lenane C">C. Wohlford-Lenane</name></author><author><name sortKey="Hickey, M" uniqKey="Hickey M">M. Hickey</name></author><author><name sortKey="Manzel, L" uniqKey="Manzel L">L. Manzel</name></author><author><name sortKey="Shi, L" uniqKey="Shi L">L. Shi</name></author><author><name sortKey="Netland, J" uniqKey="Netland J">J. Netland</name></author><author><name sortKey="Jia, H P" uniqKey="Jia H">H.P. Jia</name></author><author><name sortKey="Halabi, C" uniqKey="Halabi C">C. Halabi</name></author><author><name sortKey="Sigmund, C D" uniqKey="Sigmund C">C.D. Sigmund</name></author><author><name sortKey="Meyerholz, D K" uniqKey="Meyerholz D">D.K. Meyerholz</name></author><author><name sortKey="Kirby, P" uniqKey="Kirby P">P. Kirby</name></author><author><name sortKey="Look, D C" uniqKey="Look D">D.C. Look</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meier, C" uniqKey="Meier C">C. Meier</name></author><author><name sortKey="Aricescu, A R" uniqKey="Aricescu A">A.R. Aricescu</name></author><author><name sortKey="Assenberg, R" uniqKey="Assenberg R">R. Assenberg</name></author><author><name sortKey="Aplin, R T" uniqKey="Aplin R">R.T. Aplin</name></author><author><name sortKey="Gilbert, R J" uniqKey="Gilbert R">R.J. Gilbert</name></author><author><name sortKey="Grimes, J M" uniqKey="Grimes J">J.M. Grimes</name></author><author><name sortKey="Stuart, D I" uniqKey="Stuart D">D.I. Stuart</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mortola, E" uniqKey="Mortola E">E. Mortola</name></author><author><name sortKey="Roy, P" uniqKey="Roy P">P. Roy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nelson, C A" uniqKey="Nelson C">C.A. Nelson</name></author><author><name sortKey="Pekosz, A" uniqKey="Pekosz A">A. Pekosz</name></author><author><name sortKey="Lee, C A" uniqKey="Lee C">C.A. Lee</name></author><author><name sortKey="Diamond, M S" uniqKey="Diamond M">M.S. Diamond</name></author><author><name sortKey="Fremont, D H" uniqKey="Fremont D">D.H. Fremont</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oostra, M" uniqKey="Oostra M">M. Oostra</name></author><author><name sortKey="De Haan, C A" uniqKey="De Haan C">C.A. de Haan</name></author><author><name sortKey="De Groot, R J" uniqKey="De Groot R">R.J. de Groot</name></author><author><name sortKey="Rottier, P J" uniqKey="Rottier P">P.J. Rottier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pewe, L" uniqKey="Pewe L">L. Pewe</name></author><author><name sortKey="Zhou, H" uniqKey="Zhou H">H. Zhou</name></author><author><name sortKey="Netland, J" uniqKey="Netland J">J. Netland</name></author><author><name sortKey="Tangudu, C" uniqKey="Tangudu C">C. Tangudu</name></author><author><name sortKey="Olivares, H" uniqKey="Olivares H">H. Olivares</name></author><author><name sortKey="Shi, L" uniqKey="Shi L">L. Shi</name></author><author><name sortKey="Look, D" uniqKey="Look D">D. Look</name></author><author><name sortKey="Gallagher, T" uniqKey="Gallagher T">T. Gallagher</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reghunathan, R" uniqKey="Reghunathan R">R. Reghunathan</name></author><author><name sortKey="Jayapal, M" uniqKey="Jayapal M">M. Jayapal</name></author><author><name sortKey="Hsu, L Y" uniqKey="Hsu L">L.Y. Hsu</name></author><author><name sortKey="Chng, H H" uniqKey="Chng H">H.H. Chng</name></author><author><name sortKey="Tai, D" uniqKey="Tai D">D. Tai</name></author><author><name sortKey="Leung, B P" uniqKey="Leung B">B.P. Leung</name></author><author><name sortKey="Melendez, A J" uniqKey="Melendez A">A.J. Melendez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roberts, A" uniqKey="Roberts A">A. Roberts</name></author><author><name sortKey="Deming, D" uniqKey="Deming D">D. Deming</name></author><author><name sortKey="Paddock, C D" uniqKey="Paddock C">C.D. Paddock</name></author><author><name sortKey="Cheng, A" uniqKey="Cheng A">A. Cheng</name></author><author><name sortKey="Yount, B" uniqKey="Yount B">B. Yount</name></author><author><name sortKey="Vogel, L" uniqKey="Vogel L">L. Vogel</name></author><author><name sortKey="Herman, B D" uniqKey="Herman B">B.D. Herman</name></author><author><name sortKey="Sheahan, T" uniqKey="Sheahan T">T. Sheahan</name></author><author><name sortKey="Heise, M" uniqKey="Heise M">M. Heise</name></author><author><name sortKey="Genrich, G L" uniqKey="Genrich G">G.L. Genrich</name></author><author><name sortKey="Zaki, S R" uniqKey="Zaki S">S.R. Zaki</name></author><author><name sortKey="Baric, R" uniqKey="Baric R">R. Baric</name></author><author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K. Subbarao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rockx, B" uniqKey="Rockx B">B. Rockx</name></author><author><name sortKey="Sheahan, T" uniqKey="Sheahan T">T. Sheahan</name></author><author><name sortKey="Donaldson, E" uniqKey="Donaldson E">E. Donaldson</name></author><author><name sortKey="Harkema, J" uniqKey="Harkema J">J. Harkema</name></author><author><name sortKey="Sims, A" uniqKey="Sims A">A. Sims</name></author><author><name sortKey="Heise, M" uniqKey="Heise M">M. Heise</name></author><author><name sortKey="Pickles, R" uniqKey="Pickles R">R. Pickles</name></author><author><name sortKey="Cameron, M" uniqKey="Cameron M">M. Cameron</name></author><author><name sortKey="Kelvin, D" uniqKey="Kelvin D">D. Kelvin</name></author><author><name sortKey="Baric, R" uniqKey="Baric R">R. Baric</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rota, P A" uniqKey="Rota P">P.A. Rota</name></author><author><name sortKey="Oberste, M S" uniqKey="Oberste M">M.S. Oberste</name></author><author><name sortKey="Monroe, S S" uniqKey="Monroe S">S.S. Monroe</name></author><author><name sortKey="Nix, W A" uniqKey="Nix W">W.A. Nix</name></author><author><name sortKey="Campagnoli, R" uniqKey="Campagnoli R">R. Campagnoli</name></author><author><name sortKey="Icenogle, J P" uniqKey="Icenogle J">J.P. Icenogle</name></author><author><name sortKey="Penaranda, S" uniqKey="Penaranda S">S. Penaranda</name></author><author><name sortKey="Bankamp, B" uniqKey="Bankamp B">B. Bankamp</name></author><author><name sortKey="Maher, K" uniqKey="Maher K">K. Maher</name></author><author><name sortKey="Chen, M H" uniqKey="Chen M">M.H. Chen</name></author><author><name sortKey="Tong, S" uniqKey="Tong S">S. Tong</name></author><author><name sortKey="Tamin, A" uniqKey="Tamin A">A. Tamin</name></author><author><name sortKey="Lowe, L" uniqKey="Lowe L">L. Lowe</name></author><author><name sortKey="Frace, M" uniqKey="Frace M">M. Frace</name></author><author><name sortKey="Derisi, J L" uniqKey="Derisi J">J.L. DeRisi</name></author><author><name sortKey="Chen, Q" uniqKey="Chen Q">Q. Chen</name></author><author><name sortKey="Wang, D" uniqKey="Wang D">D. Wang</name></author><author><name sortKey="Erdman, D D" uniqKey="Erdman D">D.D. Erdman</name></author><author><name sortKey="Peret, T C" uniqKey="Peret T">T.C. Peret</name></author><author><name sortKey="Burns, C" uniqKey="Burns C">C. Burns</name></author><author><name sortKey="Ksiazek, T G" uniqKey="Ksiazek T">T.G. Ksiazek</name></author><author><name sortKey="Rollin, P E" uniqKey="Rollin P">P.E. Rollin</name></author><author><name sortKey="Sanchez, A" uniqKey="Sanchez A">A. Sanchez</name></author><author><name sortKey="Liffick, S" uniqKey="Liffick S">S. Liffick</name></author><author><name sortKey="Holloway, B" uniqKey="Holloway B">B. Holloway</name></author><author><name sortKey="Limor, J" uniqKey="Limor J">J. Limor</name></author><author><name sortKey="Mccaustland, K" uniqKey="Mccaustland K">K. McCaustland</name></author><author><name sortKey="Olsen Rasmussen, M" uniqKey="Olsen Rasmussen M">M. Olsen-Rasmussen</name></author><author><name sortKey="Fouchier, R" uniqKey="Fouchier R">R. Fouchier</name></author><author><name sortKey="Gunther, S" uniqKey="Gunther S">S. Gunther</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D. Osterhaus</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Pallansch, M A" uniqKey="Pallansch M">M.A. Pallansch</name></author><author><name sortKey="Anderson, L J" uniqKey="Anderson L">L.J. Anderson</name></author><author><name sortKey="Bellini, W J" uniqKey="Bellini W">W.J. Bellini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schaecher, S R" uniqKey="Schaecher S">S.R. Schaecher</name></author><author><name sortKey="Mackenzie, J M" uniqKey="Mackenzie J">J.M. Mackenzie</name></author><author><name sortKey="Pekosz, A" uniqKey="Pekosz A">A. Pekosz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sharma, K" uniqKey="Sharma K">K. Sharma</name></author><author><name sortKey="Surjit, M" uniqKey="Surjit M">M. Surjit</name></author><author><name sortKey="Satija, N" uniqKey="Satija N">N. Satija</name></author><author><name sortKey="Liu, B" uniqKey="Liu B">B. Liu</name></author><author><name sortKey="Chow, V T" uniqKey="Chow V">V.T. Chow</name></author><author><name sortKey="Lal, S K" uniqKey="Lal S">S.K. Lal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shen, S" uniqKey="Shen S">S. Shen</name></author><author><name sortKey="Lin, P S" uniqKey="Lin P">P.S. Lin</name></author><author><name sortKey="Chao, Y C" uniqKey="Chao Y">Y.C. Chao</name></author><author><name sortKey="Zhang, A" uniqKey="Zhang A">A. Zhang</name></author><author><name sortKey="Yang, X" uniqKey="Yang X">X. Yang</name></author><author><name sortKey="Lim, S G" uniqKey="Lim S">S.G. Lim</name></author><author><name sortKey="Hong, W" uniqKey="Hong W">W. Hong</name></author><author><name sortKey="Tan, Y J" uniqKey="Tan Y">Y.J. Tan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sims, A C" uniqKey="Sims A">A.C. Sims</name></author><author><name sortKey="Baric, R S" uniqKey="Baric R">R.S. Baric</name></author><author><name sortKey="Yount, B" uniqKey="Yount B">B. Yount</name></author><author><name sortKey="Burkett, S E" uniqKey="Burkett S">S.E. Burkett</name></author><author><name sortKey="Collins, P L" uniqKey="Collins P">P.L. Collins</name></author><author><name sortKey="Pickles, R J" uniqKey="Pickles R">R.J. Pickles</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Song, H D" uniqKey="Song H">H.D. Song</name></author><author><name sortKey="Tu, C C" uniqKey="Tu C">C.C. Tu</name></author><author><name sortKey="Zhang, G W" uniqKey="Zhang G">G.W. Zhang</name></author><author><name sortKey="Wang, S Y" uniqKey="Wang S">S.Y. Wang</name></author><author><name sortKey="Zheng, K" uniqKey="Zheng K">K. Zheng</name></author><author><name sortKey="Lei, L C" uniqKey="Lei L">L.C. Lei</name></author><author><name sortKey="Chen, Q X" uniqKey="Chen Q">Q.X. Chen</name></author><author><name sortKey="Gao, Y W" uniqKey="Gao Y">Y.W. Gao</name></author><author><name sortKey="Zhou, H Q" uniqKey="Zhou H">H.Q. Zhou</name></author><author><name sortKey="Xiang, H" uniqKey="Xiang H">H. Xiang</name></author><author><name sortKey="Zheng, H J" uniqKey="Zheng H">H.J. Zheng</name></author><author><name sortKey="Chern, S W" uniqKey="Chern S">S.W. Chern</name></author><author><name sortKey="Cheng, F" uniqKey="Cheng F">F. Cheng</name></author><author><name sortKey="Pan, C M" uniqKey="Pan C">C.M. Pan</name></author><author><name sortKey="Xuan, H" uniqKey="Xuan H">H. Xuan</name></author><author><name sortKey="Chen, S J" uniqKey="Chen S">S.J. Chen</name></author><author><name sortKey="Luo, H M" uniqKey="Luo H">H.M. Luo</name></author><author><name sortKey="Zhou, D H" uniqKey="Zhou D">D.H. Zhou</name></author><author><name sortKey="Liu, Y F" uniqKey="Liu Y">Y.F. Liu</name></author><author><name sortKey="He, J F" uniqKey="He J">J.F. He</name></author><author><name sortKey="Qin, P Z" uniqKey="Qin P">P.Z. Qin</name></author><author><name sortKey="Li, L H" uniqKey="Li L">L.H. Li</name></author><author><name sortKey="Ren, Y Q" uniqKey="Ren Y">Y.Q. Ren</name></author><author><name sortKey="Liang, W J" uniqKey="Liang W">W.J. Liang</name></author><author><name sortKey="Yu, Y D" uniqKey="Yu Y">Y.D. Yu</name></author><author><name sortKey="Anderson, L" uniqKey="Anderson L">L. Anderson</name></author><author><name sortKey="Wang, M" uniqKey="Wang M">M. Wang</name></author><author><name sortKey="Xu, R H" uniqKey="Xu R">R.H. Xu</name></author><author><name sortKey="Wu, X W" uniqKey="Wu X">X.W. Wu</name></author><author><name sortKey="Zheng, H Y" uniqKey="Zheng H">H.Y. Zheng</name></author><author><name sortKey="Chen, J D" uniqKey="Chen J">J.D. Chen</name></author><author><name sortKey="Liang, G" uniqKey="Liang G">G. Liang</name></author><author><name sortKey="Gao, Y" uniqKey="Gao Y">Y. Gao</name></author><author><name sortKey="Liao, M" uniqKey="Liao M">M. Liao</name></author><author><name sortKey="Fang, L" uniqKey="Fang L">L. Fang</name></author><author><name sortKey="Jiang, L Y" uniqKey="Jiang L">L.Y. Jiang</name></author><author><name sortKey="Li, H" uniqKey="Li H">H. Li</name></author><author><name sortKey="Chen, F" uniqKey="Chen F">F. Chen</name></author><author><name sortKey="Di, B" uniqKey="Di B">B. Di</name></author><author><name sortKey="He, L J" uniqKey="He L">L.J. He</name></author><author><name sortKey="Lin, J Y" uniqKey="Lin J">J.Y. Lin</name></author><author><name sortKey="Tong, S" uniqKey="Tong S">S. Tong</name></author><author><name sortKey="Kong, X" uniqKey="Kong X">X. Kong</name></author><author><name sortKey="Du, L" uniqKey="Du L">L. Du</name></author><author><name sortKey="Hao, P" uniqKey="Hao P">P. Hao</name></author><author><name sortKey="Tang, H" uniqKey="Tang H">H. Tang</name></author><author><name sortKey="Bernini, A" uniqKey="Bernini A">A. Bernini</name></author><author><name sortKey="Yu, X J" uniqKey="Yu X">X.J. Yu</name></author><author><name sortKey="Spiga, O" uniqKey="Spiga O">O. Spiga</name></author><author><name sortKey="Guo, Z M" uniqKey="Guo Z">Z.M. Guo</name></author><author><name sortKey="Pan, H Y" uniqKey="Pan H">H.Y. Pan</name></author><author><name sortKey="He, W Z" uniqKey="He W">W.Z. He</name></author><author><name sortKey="Manuguerra, J C" uniqKey="Manuguerra J">J.C. Manuguerra</name></author><author><name sortKey="Fontanet, A" uniqKey="Fontanet A">A. Fontanet</name></author><author><name sortKey="Danchin, A" uniqKey="Danchin A">A. Danchin</name></author><author><name sortKey="Niccolai, N" uniqKey="Niccolai N">N. Niccolai</name></author><author><name sortKey="Li, Y X" uniqKey="Li Y">Y.X. Li</name></author><author><name sortKey="Wu, C I" uniqKey="Wu C">C.I. Wu</name></author><author><name sortKey="Zhao, G P" uniqKey="Zhao G">G.P. Zhao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Spiegel, M" uniqKey="Spiegel M">M. Spiegel</name></author><author><name sortKey="Pichlmair, A" uniqKey="Pichlmair A">A. Pichlmair</name></author><author><name sortKey="Martinez Sobrido, L" uniqKey="Martinez Sobrido L">L. Martinez-Sobrido</name></author><author><name sortKey="Cros, J" uniqKey="Cros J">J. Cros</name></author><author><name sortKey="Garcia Sastre, A" uniqKey="Garcia Sastre A">A. Garcia-Sastre</name></author><author><name sortKey="Haller, O" uniqKey="Haller O">O. Haller</name></author><author><name sortKey="Weber, F" uniqKey="Weber F">F. Weber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K. Subbarao</name></author><author><name sortKey="Mcauliffe, J" uniqKey="Mcauliffe J">J. McAuliffe</name></author><author><name sortKey="Vogel, L" uniqKey="Vogel L">L. Vogel</name></author><author><name sortKey="Fahle, G" uniqKey="Fahle G">G. Fahle</name></author><author><name sortKey="Fischer, S" uniqKey="Fischer S">S. Fischer</name></author><author><name sortKey="Tatti, K" uniqKey="Tatti K">K. Tatti</name></author><author><name sortKey="Packard, M" uniqKey="Packard M">M. Packard</name></author><author><name sortKey="Shieh, W J" uniqKey="Shieh W">W.J. Shieh</name></author><author><name sortKey="Zaki, S" uniqKey="Zaki S">S. Zaki</name></author><author><name sortKey="Murphy, B" uniqKey="Murphy B">B. Murphy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K. Subbarao</name></author><author><name sortKey="Roberts, A" uniqKey="Roberts A">A. Roberts</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tan, Y J" uniqKey="Tan Y">Y.J. Tan</name></author><author><name sortKey="Fielding, B C" uniqKey="Fielding B">B.C. Fielding</name></author><author><name sortKey="Goh, P Y" uniqKey="Goh P">P.Y. Goh</name></author><author><name sortKey="Shen, S" uniqKey="Shen S">S. Shen</name></author><author><name sortKey="Tan, T H" uniqKey="Tan T">T.H. Tan</name></author><author><name sortKey="Lim, S G" uniqKey="Lim S">S.G. Lim</name></author><author><name sortKey="Hong, W" uniqKey="Hong W">W. Hong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tan, Y J" uniqKey="Tan Y">Y.J. Tan</name></author><author><name sortKey="Goh, P Y" uniqKey="Goh P">P.Y. Goh</name></author><author><name sortKey="Fielding, B C" uniqKey="Fielding B">B.C. Fielding</name></author><author><name sortKey="Shen, S" uniqKey="Shen S">S. Shen</name></author><author><name sortKey="Chou, C F" uniqKey="Chou C">C.F. Chou</name></author><author><name sortKey="Fu, J L" uniqKey="Fu J">J.L. Fu</name></author><author><name sortKey="Leong, H N" uniqKey="Leong H">H.N. Leong</name></author><author><name sortKey="Leo, Y S" uniqKey="Leo Y">Y.S. Leo</name></author><author><name sortKey="Ooi, E E" uniqKey="Ooi E">E.E. Ooi</name></author><author><name sortKey="Ling, A E" uniqKey="Ling A">A.E. Ling</name></author><author><name sortKey="Lim, S G" uniqKey="Lim S">S.G. Lim</name></author><author><name sortKey="Hong, W" uniqKey="Hong W">W. Hong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tan, Y J" uniqKey="Tan Y">Y.J. Tan</name></author><author><name sortKey="Teng, E" uniqKey="Teng E">E. Teng</name></author><author><name sortKey="Shen, S" uniqKey="Shen S">S. Shen</name></author><author><name sortKey="Tan, T H" uniqKey="Tan T">T.H. Tan</name></author><author><name sortKey="Goh, P Y" uniqKey="Goh P">P.Y. Goh</name></author><author><name sortKey="Fielding, B C" uniqKey="Fielding B">B.C. Fielding</name></author><author><name sortKey="Ooi, E E" uniqKey="Ooi E">E.E. Ooi</name></author><author><name sortKey="Tan, H C" uniqKey="Tan H">H.C. Tan</name></author><author><name sortKey="Lim, S G" uniqKey="Lim S">S.G. Lim</name></author><author><name sortKey="Hong, W" uniqKey="Hong W">W. Hong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tan, Y J" uniqKey="Tan Y">Y.J. Tan</name></author><author><name sortKey="Tham, P Y" uniqKey="Tham P">P.Y. Tham</name></author><author><name sortKey="Chan, D Z" uniqKey="Chan D">D.Z. Chan</name></author><author><name sortKey="Chou, C F" uniqKey="Chou C">C.F. Chou</name></author><author><name sortKey="Shen, S" uniqKey="Shen S">S. Shen</name></author><author><name sortKey="Fielding, B C" uniqKey="Fielding B">B.C. Fielding</name></author><author><name sortKey="Tan, T H" uniqKey="Tan T">T.H. Tan</name></author><author><name sortKey="Lim, S G" uniqKey="Lim S">S.G. Lim</name></author><author><name sortKey="Hong, W" uniqKey="Hong W">W. Hong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tang, B S" uniqKey="Tang B">B.S. Tang</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Cheng, V C" uniqKey="Cheng V">V.C. Cheng</name></author><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Lam, C C" uniqKey="Lam C">C.C. Lam</name></author><author><name sortKey="Chan, T L" uniqKey="Chan T">T.L. Chan</name></author><author><name sortKey="Wu, A K" uniqKey="Wu A">A.K. Wu</name></author><author><name sortKey="Hung, I F" uniqKey="Hung I">I.F. Hung</name></author><author><name sortKey="Leung, S Y" uniqKey="Leung S">S.Y. Leung</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tangudu, C" uniqKey="Tangudu C">C. Tangudu</name></author><author><name sortKey="Olivares, H" uniqKey="Olivares H">H. Olivares</name></author><author><name sortKey="Netland, J" uniqKey="Netland J">J. Netland</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author><author><name sortKey="Gallagher, T" uniqKey="Gallagher T">T. Gallagher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thiel, V" uniqKey="Thiel V">V. Thiel</name></author><author><name sortKey="Ivanov, K A" uniqKey="Ivanov K">K.A. Ivanov</name></author><author><name sortKey="Putics, A" uniqKey="Putics A">A. Putics</name></author><author><name sortKey="Hertzig, T" uniqKey="Hertzig T">T. Hertzig</name></author><author><name sortKey="Schelle, B" uniqKey="Schelle B">B. Schelle</name></author><author><name sortKey="Bayer, S" uniqKey="Bayer S">S. Bayer</name></author><author><name sortKey="Weissbrich, B" uniqKey="Weissbrich B">B. Weissbrich</name></author><author><name sortKey="Snijder, E J" uniqKey="Snijder E">E.J. Snijder</name></author><author><name sortKey="Rabenau, H" uniqKey="Rabenau H">H. Rabenau</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W. Doerr</name></author><author><name sortKey="Gorbalenya, A E" uniqKey="Gorbalenya A">A.E. Gorbalenya</name></author><author><name sortKey="Ziebuhr, J" uniqKey="Ziebuhr J">J. Ziebuhr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tseng, C T" uniqKey="Tseng C">C.T. Tseng</name></author><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Newman, P" uniqKey="Newman P">P. Newman</name></author><author><name sortKey="Wang, N" uniqKey="Wang N">N. Wang</name></author><author><name sortKey="Narayanan, K" uniqKey="Narayanan K">K. Narayanan</name></author><author><name sortKey="Watts, D M" uniqKey="Watts D">D.M. Watts</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author><author><name sortKey="Packard, M M" uniqKey="Packard M">M.M. Packard</name></author><author><name sortKey="Zaki, S R" uniqKey="Zaki S">S.R. Zaki</name></author><author><name sortKey="Chan, T S" uniqKey="Chan T">T.S. Chan</name></author><author><name sortKey="Peters, C J" uniqKey="Peters C">C.J. Peters</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wesley, R D" uniqKey="Wesley R">R.D. Wesley</name></author><author><name sortKey="Woods, R D" uniqKey="Woods R">R.D. Woods</name></author><author><name sortKey="Cheung, A K" uniqKey="Cheung A">A.K. Cheung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yount, B" uniqKey="Yount B">B. Yount</name></author><author><name sortKey="Curtis, K M" uniqKey="Curtis K">K.M. Curtis</name></author><author><name sortKey="Fritz, E A" uniqKey="Fritz E">E.A. Fritz</name></author><author><name sortKey="Hensley, L E" uniqKey="Hensley L">L.E. Hensley</name></author><author><name sortKey="Jahrling, P B" uniqKey="Jahrling P">P.B. Jahrling</name></author><author><name sortKey="Prentice, E" uniqKey="Prentice E">E. Prentice</name></author><author><name sortKey="Denison, M R" uniqKey="Denison M">M.R. Denison</name></author><author><name sortKey="Geisbert, T W" uniqKey="Geisbert T">T.W. Geisbert</name></author><author><name sortKey="Baric, R S" uniqKey="Baric R">R.S. Baric</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yount, B" uniqKey="Yount B">B. Yount</name></author><author><name sortKey="Roberts, R S" uniqKey="Roberts R">R.S. Roberts</name></author><author><name sortKey="Sims, A C" uniqKey="Sims A">A.C. Sims</name></author><author><name sortKey="Deming, D" uniqKey="Deming D">D. Deming</name></author><author><name sortKey="Frieman, M B" uniqKey="Frieman M">M.B. Frieman</name></author><author><name sortKey="Sparks, J" uniqKey="Sparks J">J. Sparks</name></author><author><name sortKey="Denison, M R" uniqKey="Denison M">M.R. Denison</name></author><author><name sortKey="Davis, N" uniqKey="Davis N">N. Davis</name></author><author><name sortKey="Baric, R S" uniqKey="Baric R">R.S. Baric</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yuan, X" uniqKey="Yuan X">X. Yuan</name></author><author><name sortKey="Li, J" uniqKey="Li J">J. Li</name></author><author><name sortKey="Shan, Y" uniqKey="Shan Y">Y. Shan</name></author><author><name sortKey="Yang, Z" uniqKey="Yang Z">Z. Yang</name></author><author><name sortKey="Zhao, Z" uniqKey="Zhao Z">Z. Zhao</name></author><author><name sortKey="Chen, B" uniqKey="Chen B">B. Chen</name></author><author><name sortKey="Yao, Z" uniqKey="Yao Z">Z. Yao</name></author><author><name sortKey="Dong, B" uniqKey="Dong B">B. Dong</name></author><author><name sortKey="Wang, S" uniqKey="Wang S">S. Wang</name></author><author><name sortKey="Chen, J" uniqKey="Chen J">J. Chen</name></author><author><name sortKey="Cong, Y" uniqKey="Cong Y">Y. Cong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yuan, X" uniqKey="Yuan X">X. Yuan</name></author><author><name sortKey="Shan, Y" uniqKey="Shan Y">Y. Shan</name></author><author><name sortKey="Yao, Z" uniqKey="Yao Z">Z. Yao</name></author><author><name sortKey="Li, J" uniqKey="Li J">J. Li</name></author><author><name sortKey="Zhao, Z" uniqKey="Zhao Z">Z. Zhao</name></author><author><name sortKey="Chen, J" uniqKey="Chen J">J. Chen</name></author><author><name sortKey="Cong, Y" uniqKey="Cong Y">Y. Cong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yuan, X" uniqKey="Yuan X">X. Yuan</name></author><author><name sortKey="Shan, Y" uniqKey="Shan Y">Y. Shan</name></author><author><name sortKey="Zhao, Z" uniqKey="Zhao Z">Z. Zhao</name></author><author><name sortKey="Chen, J" uniqKey="Chen J">J. Chen</name></author><author><name sortKey="Cong, Y" uniqKey="Cong Y">Y. Cong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yuan, X" uniqKey="Yuan X">X. Yuan</name></author><author><name sortKey="Wu, J" uniqKey="Wu J">J. Wu</name></author><author><name sortKey="Shan, Y" uniqKey="Shan Y">Y. Shan</name></author><author><name sortKey="Yao, Z" uniqKey="Yao Z">Z. Yao</name></author><author><name sortKey="Dong, B" uniqKey="Dong B">B. Dong</name></author><author><name sortKey="Chen, B" uniqKey="Chen B">B. Chen</name></author><author><name sortKey="Zhao, Z" uniqKey="Zhao Z">Z. Zhao</name></author><author><name sortKey="Wang, S" uniqKey="Wang S">S. Wang</name></author><author><name sortKey="Chen, J" uniqKey="Chen J">J. Chen</name></author><author><name sortKey="Cong, Y" uniqKey="Cong Y">Y. Cong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yuan, X" uniqKey="Yuan X">X. Yuan</name></author><author><name sortKey="Yao, Z" uniqKey="Yao Z">Z. Yao</name></author><author><name sortKey="Shan, Y" uniqKey="Shan Y">Y. Shan</name></author><author><name sortKey="Chen, B" uniqKey="Chen B">B. Chen</name></author><author><name sortKey="Yang, Z" uniqKey="Yang Z">Z. Yang</name></author><author><name sortKey="Wu, J" uniqKey="Wu J">J. Wu</name></author><author><name sortKey="Zhao, Z" uniqKey="Zhao Z">Z. Zhao</name></author><author><name sortKey="Chen, J" uniqKey="Chen J">J. Chen</name></author><author><name sortKey="Cong, Y" uniqKey="Cong Y">Y. Cong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yuan, X" uniqKey="Yuan X">X. Yuan</name></author><author><name sortKey="Yao, Z" uniqKey="Yao Z">Z. Yao</name></author><author><name sortKey="Wu, J" uniqKey="Wu J">J. Wu</name></author><author><name sortKey="Zhou, Y" uniqKey="Zhou Y">Y. Zhou</name></author><author><name sortKey="Shan, Y" uniqKey="Shan Y">Y. Shan</name></author><author><name sortKey="Dong, B" uniqKey="Dong B">B. Dong</name></author><author><name sortKey="Zhao, Z" uniqKey="Zhao Z">Z. Zhao</name></author><author><name sortKey="Hua, P" uniqKey="Hua P">P. Hua</name></author><author><name sortKey="Chen, J" uniqKey="Chen J">J. Chen</name></author><author><name sortKey="Cong, Y" uniqKey="Cong Y">Y. Cong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zeng, R" uniqKey="Zeng R">R. Zeng</name></author><author><name sortKey="Yang, R F" uniqKey="Yang R">R.F. Yang</name></author><author><name sortKey="Shi, M D" uniqKey="Shi M">M.D. Shi</name></author><author><name sortKey="Jiang, M R" uniqKey="Jiang M">M.R. Jiang</name></author><author><name sortKey="Xie, Y H" uniqKey="Xie Y">Y.H. Xie</name></author><author><name sortKey="Ruan, H Q" uniqKey="Ruan H">H.Q. Ruan</name></author><author><name sortKey="Jiang, X S" uniqKey="Jiang X">X.S. Jiang</name></author><author><name sortKey="Shi, L" uniqKey="Shi L">L. Shi</name></author><author><name sortKey="Zhou, H" uniqKey="Zhou H">H. Zhou</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name></author><author><name sortKey="Wu, X D" uniqKey="Wu X">X.D. Wu</name></author><author><name sortKey="Lin, Y" uniqKey="Lin Y">Y. Lin</name></author><author><name sortKey="Ji, Y Y" uniqKey="Ji Y">Y.Y. Ji</name></author><author><name sortKey="Xiong, L" uniqKey="Xiong L">L. Xiong</name></author><author><name sortKey="Jin, Y" uniqKey="Jin Y">Y. Jin</name></author><author><name sortKey="Dai, E H" uniqKey="Dai E">E.H. Dai</name></author><author><name sortKey="Wang, X Y" uniqKey="Wang X">X.Y. Wang</name></author><author><name sortKey="Si, B Y" uniqKey="Si B">B.Y. Si</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J. Wang</name></author><author><name sortKey="Wang, H X" uniqKey="Wang H">H.X. Wang</name></author><author><name sortKey="Wang, C E" uniqKey="Wang C">C.E. Wang</name></author><author><name sortKey="Gan, Y H" uniqKey="Gan Y">Y.H. Gan</name></author><author><name sortKey="Li, Y C" uniqKey="Li Y">Y.C. Li</name></author><author><name sortKey="Cao, J T" uniqKey="Cao J">J.T. Cao</name></author><author><name sortKey="Zuo, J P" uniqKey="Zuo J">J.P. Zuo</name></author><author><name sortKey="Shan, S F" uniqKey="Shan S">S.F. Shan</name></author><author><name sortKey="Xie, E" uniqKey="Xie E">E. Xie</name></author><author><name sortKey="Chen, S H" uniqKey="Chen S">S.H. Chen</name></author><author><name sortKey="Jiang, Z Q" uniqKey="Jiang Z">Z.Q. Jiang</name></author><author><name sortKey="Zhang, X" uniqKey="Zhang X">X. Zhang</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Pei, G" uniqKey="Pei G">G. Pei</name></author><author><name sortKey="Sun, B" uniqKey="Sun B">B. Sun</name></author><author><name sortKey="Wu, J R" uniqKey="Wu J">J.R. Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y. Zhang</name></author><author><name sortKey="Li, J" uniqKey="Li J">J. Li</name></author><author><name sortKey="Zhan, Y" uniqKey="Zhan Y">Y. Zhan</name></author><author><name sortKey="Wu, L" uniqKey="Wu L">L. Wu</name></author><author><name sortKey="Yu, X" uniqKey="Yu X">X. Yu</name></author><author><name sortKey="Zhang, W" uniqKey="Zhang W">W. Zhang</name></author><author><name sortKey="Ye, L" uniqKey="Ye L">L. Ye</name></author><author><name sortKey="Xu, S" uniqKey="Xu S">S. Xu</name></author><author><name sortKey="Sun, R" uniqKey="Sun R">R. Sun</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Lou, J" uniqKey="Lou J">J. Lou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhong, X" uniqKey="Zhong X">X. Zhong</name></author><author><name sortKey="Guo, Z" uniqKey="Guo Z">Z. Guo</name></author><author><name sortKey="Yang, H" uniqKey="Yang H">H. Yang</name></author><author><name sortKey="Peng, L" uniqKey="Peng L">L. Peng</name></author><author><name sortKey="Xie, Y" uniqKey="Xie Y">Y. Xie</name></author><author><name sortKey="Wong, T Y" uniqKey="Wong T">T.Y. Wong</name></author><author><name sortKey="Lai, S T" uniqKey="Lai S">S.T. Lai</name></author><author><name sortKey="Guo, Z" uniqKey="Guo Z">Z. Guo</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Virus Res</journal-id><journal-id journal-id-type="iso-abbrev">Virus Res</journal-id><journal-title-group><journal-title>Virus Research</journal-title></journal-title-group><issn pub-type="ppub">0168-1702</issn><issn pub-type="epub">1872-7492</issn><publisher><publisher-name>Elsevier B.V.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">18045721</article-id><article-id pub-id-type="pmc">2720074</article-id><article-id pub-id-type="publisher-id">S0168-1702(07)00371-1</article-id><article-id pub-id-type="doi">10.1016/j.virusres.2007.10.009</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>SARS coronavirus accessory proteins</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Narayanan</surname><given-names>Krishna</given-names></name><email>krnaraya@utmb.edu</email><xref rid="cor1" ref-type="corresp">⁎</xref></contrib><contrib contrib-type="author"><name><surname>Huang</surname><given-names>Cheng</given-names></name><email>chhuang@utmb.edu</email><xref rid="fn1" ref-type="fn">1</xref></contrib><contrib contrib-type="author"><name><surname>Makino</surname><given-names>Shinji</given-names></name><email>shmakino@utmb.edu</email><xref rid="fn2" ref-type="fn">2</xref></contrib></contrib-group><aff>Department of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555-1019, United States</aff><author-notes><corresp id="cor1"><label>⁎</label>Corresponding author. Tel.: +1 409 772 8172; fax: +1 409 772 5065. <email>krnaraya@utmb.edu</email></corresp><fn id="fn1"><label>1</label><p>Tel.: +1 409 772 8172.</p></fn><fn id="fn2"><label>2</label><p>Tel.: +1 409 772 2323.</p></fn></author-notes><pub-date pub-type="pmc-release"><day>28</day><month>11</month><year>2007</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>4</month><year>2008</year></pub-date><pub-date pub-type="epub"><day>28</day><month>11</month><year>2007</year></pub-date><volume>133</volume><issue>1</issue><fpage>113</fpage><lpage>121</lpage><permissions><copyright-statement>Copyright © 2007 Elsevier B.V. All rights reserved.</copyright-statement><copyright-year>2007</copyright-year><copyright-holder>Elsevier B.V.</copyright-holder><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract><p>The emergence of the severe acute respiratory syndrome coronavirus (SARS-CoV) has led to a renewed interest in studying the role of accessory proteins in regulating coronavirus infections in the natural host. A significant body of evidence has accumulated in the area of SARS-CoV and host interactions that indicate that the accessory proteins might play an important role in modulating the host response to virus infection and thereby, contribute to pathogenesis. In this review, we have compiled the current knowledge about SARS-CoV accessory proteins, obtained from studies in cell culture systems, reverse genetics and animal models, to shed some light into the possible role of these proteins in the propagation and virulence of SARS-CoV in its natural host. We conclude by providing some questions for future studies that will greatly advance our knowledge about the biological significance and contributions of the accessory proteins in the development of SARS in humans.</p></abstract><kwd-group><title>Keywords</title><kwd>RNA viruses</kwd><kwd>SARS coronavirus</kwd><kwd>SARS-CoV</kwd><kwd>Accessory proteins</kwd></kwd-group></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Huang, Cheng" sort="Huang, Cheng" uniqKey="Huang C" first="Cheng" last="Huang">Cheng Huang</name><name sortKey="Makino, Shinji" sort="Makino, Shinji" uniqKey="Makino S" first="Shinji" last="Makino">Shinji Makino</name><name sortKey="Narayanan, Krishna" sort="Narayanan, Krishna" uniqKey="Narayanan K" first="Krishna" last="Narayanan">Krishna Narayanan</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Pmc/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000F05 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd -nk 000F05 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Pmc
|étape= Checkpoint
|type= RBID
|clé= PMC:2720074
|texte= SARS coronavirus accessory proteins
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/RBID.i -Sk "pubmed:18045721" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |